Real Madrid vs Juventus (Champions League): odds and picks 22.10.2025

I have a clear feeling about this match. Real Madrid are in good form going into this edition of the 2025-26 UEFA Champions League: they have won their first group matches, which gives them confidence going into this home game.

Juventus, on the other hand, arrive with more doubts: they have drawn their matches and have not got off to the start they would have liked in Europe and in the league, which could work against them.

Both teams have a history with each other, but Real Madrid has dominated recent encounters: of the last 11 matches, they have won 6, Juve 3, and there have been 2 draws. This gives Madrid a psychological advantage, especially playing at home.

Even so, Juventus has the ability to compete at key moments and could pose a threat on the counterattack or in transitional phases.

Date, time and where to watch the match

• Competition: UEFA Champions League
• Date: Wednesday 22 October 2025

Odds for the winner of Real Madrid vs Juventus

Real Madrid analysis

Real Madrid are in good form: they have remained solid in attack and have a strong home record. They have performed well in the Champions League this season and their squad gives them an advantage over many of their rivals.

Key players

• Kylian Mbappé: His offensive contribution has been decisive for the team this season, both in terms of goals and playmaking. His presence makes a difference.
• Jude Bellingham: Although he scores fewer goals than Mbappé, his control of the midfield, arrival in the box and link-up play make him a key factor in breaking down defences that close down, as Juventus could do.

Real Madrid’s current situation in the competition

In this season’s Champions League, they have started with victories against Marseille and Kairat, which allows them to approach this match with more confidence. Their goal average is high and their defence has been relatively solid.

At home, they are even more dominant: they have the upper hand in matches against Juventus and in their home record, which reinforces their favouritism.

Juventus analysis

Juventus arrive needing to improve. Their start to the Champions League has not been ideal (draws) and they have also had inconsistent results in the league, which creates some pressure against such demanding opponents.

Key players

• Dusan Vlahović: As the leading striker, he has the task of making the difference in attack, and his effectiveness will be vital if Juventus are to have any chance.
• Kenan Yıldız: A young emerging talent in the team who has started the season well. His impact could give the Italian side some attacking impetus.

Juventus’ current situation in the competition

They have failed to get off to a winning start in the Champions League (drawing against Villarreal and Borussia Dortmund), which means they now have to be more aggressive. Losing this match could leave them with little room for error in the group.

Their defence has shown room for improvement, and facing a rival of Madrid’s stature at their home ground requires maximum concentration.

Real Madrid vs Juventus: head-to-head record

As I mentioned earlier, the historical balance favours Real Madrid: of the last 11 head-to-head matches, Madrid have won six, Juventus three and there have been two draws.

This historical superiority, coupled with the fact that they are playing at home, gives Madrid a tangible advantage.

In addition, matches between the two sides tend to be high-scoring: the average number of goals in their encounters is around 3.18 per game, and in approximately 73% of cases, both teams have scored at least once.

Summary: key facts

• Real Madrid are clear favourites, especially playing at home.
• Juventus arrive needing a good performance and under pressure, which could generate both motivation and mistakes.
• The history between the two sides favours Madrid, both statistically and in terms of context and timing.
• Matches between them tend to have several goals and both teams are accustomed to scoring.
• If Juventus sits back too much, Madrid has the resources to create and exploit space; if Juventus dares to attack, it can cause damage on the counter.

My prediction for Real Madrid vs Juventus

As an estimate, a plausible score could be 3-1 or 2-1 in favour of Real Madrid.