Real Betis vs Lyon (Europa League): odds and picks 06.11.2025

Europa League match (group stage, Matchday 4) on Thursday, 6 November 2025, at the Estadio Olímpico de La Cartuja (Seville).

Betis arrive with their home work done and a recent surge in goals; Lyon arrive with a clean European sheet in this phase and a streak of solidity at the back.

Useful context: in the most recent European H2H, 2013/14 season, it was 0-0 in Seville and 1-0 in Lyon (group stage).

Real Betis

Betis are competing with skill and are turning long periods of possession into chances. In the league, their defensive record is solid (averaging close to 0.7 goals conceded per game in Europe) and at home they are producing a lot of attacking play, helped by the wide pitch at La Cartuja.

In recent games, Pellegrini’s team has alternated between very controlled matches and bursts of attacking flair (the 7-1 cup win was a sign that the goals are flowing).

Key factors I value:

• Set pieces with centre-backs coming in strong.
• Managing losses in the middle to prevent transitions.
• Activating the left wing to attack the far post.

If Betis scores first, they know how to manage their advantage without breaking down.

Olympique Lyon

Fonseca’s side are looking very solid in Europe: 3-0-0 after three games, 0 goals conceded in the phase and an average of 1.67 goals scored. Their recent record includes away draws (0-0 in Brest), high-scoring games (3-3 in Paris) and narrow home wins.

In their European pattern, Lyon clear their own area well (100% of matches without conceding) and attack judiciously, generating an average xG of 1.6 and xGA of 1.16.

Key points in Seville:

• Protect the full-back’s lane against dangerous crosses.
• Sustain second plays.
• Gain height in pressing with the double pivot to cut off Betis’ circulation.

If the game speeds up, Lyon suffers less than in Ligue 1 because they are defending their area better in Europe.

My predictions for Betis vs Lyon

BeniThe conservative one

Under 3.0 goals (Asian). Odds 1.60.

Lyon arrive with 0 goals conceded in 3 European games and a cautious away plan; Betis, despite their attacking style, tend to control the pace in Europe and do not lose their composure if they are ahead.
Compatible scores: 1-0, 1-1, 2-0. Even safer version: Under 3.25 (odds ~1.45), which returns half if there are exactly 3 goals.

BetoThe bold one

Betis wins & Under 3.5 goals. Odds 2.90.

At La Cartuja, Betis manages its advantages well, and Lyon has been rock solid in Europe. I see a narrow home win if the first goal goes to the Green and Whites and the match settles into controlled possession (1-0, 2-0 or 2-1). As a medium-risk alternative: Betis -0.25 Asian handicap at 1.95–2.05 (you win half if they win by 1, you get half back if it’s a draw).