Czech Republic vs Spain Prediction: UEFA Nations League Betting Tips and Odds 12.11.2026

Czechia have endured a difficult Nations League campaign under Santi Denia, losing all four group matches. They began with a 2-1 home defeat against Croatia before losing 2-0 to England. Spain then beat them 3-1 in Oviedo, followed by a 3-0 defeat at Wembley. Czechia have scored just twice and conceded ten goals, allowing at least two in every match. Their team news offers some encouragement. West Ham midfielder Tomáš Souček returns after recovering from an ankle injury, while David Jurásek, David Zima and Lukáš Provod are also back in the squad.

Adam Hložek has been selected despite a recent muscular problem. Denia confirmed that all 24 called-up players had medical clearance when the squad was announced, although their final availability should still be monitored. Pavel Šulc is absent through injury, removing an attacking option from a side already struggling to create goals. Czechia should benefit from Souček’s presence, particularly in midfield battles and set-piece situations. However, their defensive record makes this another difficult assignment.

Spain have won all four Nations League matches, scoring 12 goals and conceding five. De la Fuente’s side opened with a 3-2 victory away to England, followed by a 4-1 home win against Croatia. They then defeated Czechia 3-1 before securing another away victory, beating Croatia 2-1. That’s an impressive record against England, Croatia and Czechia, with Spain scoring at least twice in every fixture.

Their November squad includes Lamine Yamal, Nico Williams, Mikel Oyarzabal, Pedri and Martín Zubimendi. Rodri is not among the 27 selected players. Spain have already secured their quarter-final place, but Sunday’s meeting with England could determine who tops Group A3. That creates a selection consideration. De la Fuente may manage playing time across the two fixtures, making the confirmed starting XI important before kick-off. Nevertheless, Spain’s attacking depth and away performances make them clear favourites in Prague.

1. Spain’s Perfect Group Record: Four victories from four matches, including away wins against England and Croatia, show that Spain’s results have come against strong opposition.
2. Czechia’s Defensive Weaknesses: The hosts have conceded ten goals in four games, allowing at least twice in every fixture. Spain’s passing and movement should create further opportunities.
3. Souček’s Return and Šulc’s Absence: Souček provides experience and a set-piece threat, but losing Šulc limits Czechia’s attacking options.
4. Spain’s Scoring Consistency: Every Spain group match has produced at least three goals. The visitors have scored 12, averaging three per game.
5. Spain’s Upcoming England Fixture: The visitors have already qualified for the quarter-finals but still want to finish first. The short turnaround before facing England makes team selection worth monitoring.